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Get a load of Jason Mecier's portraits of celebrities Amy Winehouse, Michael Jackson, Heath Ledger, Courtney Love and Kelly Osbourne made with actual pills. While it's true that some of these subject's undoing was the medium itself, others, like Kelly Osbourne have successfully kicked the habit. Either way, these are interesting homages to them.
Be sure to check out the Red Vine, Candy and Junk mosaic portraits by this same artist, Jason Mecier and the self portrait comprised of Ecstacy tablets by bar code artist Scott Blake.